产品编号:100201
产品英文名:Phenol
EMPROVE® ESSENTIAL Ph Eur,ChP,JP,USP
产品中文名:苯酚
药物用途:
苯酚为一种原浆毒,能使细菌细胞的原生质蛋白发生凝固或变性而杀菌。浓度约0.2%即有抑菌作用,大于1%能杀死一般细菌,1.3%溶液可杀死真菌。本品稀溶液可使人体感觉神经末梢麻痹,产生局部麻醉作用,可止痒。苯酚对组织的穿透性强,易从皮肤黏膜及创面吸收,故不宜大面积长期使用。酚软膏(2%)用于皮肤防腐止痒。 




苯酚Phenol
规格
Assay (bromatometric) 99.0 - 100.5 %
Assay (bromatometric, calc. on anhydrous substance) 99.0 - 100.5 %
Identity (IR-spectrum) passes test
Identity (wet chemistry) passes test
Appearance colourless or faintly pink or faintly yellowish crystals or crystalline masses, deliquescent
Appearance of solution (67 g/l, water) clear and not more intensely coloured than reference solution B6
Acidic substances passes test
Solidification temperature ≥ 39.5 °C
Fe (Iron) ≤ 1 ppm
Benzene (HS-GC) ≤ 2 ppm
Methanol (HS-GC) ≤ 3000 ppm
Acetone (HS-GC) ≤ 2 ppm
Anisole ≤ 10 ppm
Cumene (HS-GC) ≤ 70 ppm
Methylisobutylketone (HS-GC) ≤ 2 ppm
Other residual solvents (ICH (Q3C)) excluded by manufacturing process
Residue on evaporation (105 °C, 1 h) ≤ 0.05 %
Residue on evaporation (105 °C) ≤ 0.05 %
Water (according to Karl Fischer) ≤ 0.5 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., ChP, JP, USP