对固体制剂来说,API的溶出度是关键的质量指标。为了优化产品配方,我们研发了一个新的创新材料拥有独一无二的表面结构,以提高API的载药性能。并且这一创新并不会引起法规方面更多的要求。得益于独一无二的多孔结构,Parteck® SLC在口服固体制剂中载入无定型的API,显著地提高API的溶出度。

 

使用Parteck®SLC作为新的配方工具,可以对很多药用分子进行再开发。由于越来越多的药品专利过期,对药品的再开发,可以显著地增强你对产品生命周期的管理。

 

用于药物传递的Parteck® SLC是我们为了最大化载药和最大化释放而提出的解决方案,最终是为了提高API的生物利用度。因为每一份药品都是珍贵的。

 

Parteck® SLC可以提供:

优异的溶出表现

对使用者友好的粒径

 

可靠的供应链以及应用支持

多孔硅载体Parteck®SLC
Description
Catalogue Number 120091
Description Parteck® SLC 500
Product Information
CAS number 7631-86-9
EC number 231-545-4
Grade USP,Ph.Eur.
Hill Formula O₂Si
Chemical formula SiO₂
Molar Mass 60.08 g/mol
HS Code 2811 22 00
Applications
Application Parteck® SLC 500 USP,Ph.Eur. CAS 7631-86-9, EC Number 231-545-4, chemical formula SiO₂.
Physicochemical Information
Melting Point 1710 °C
pH value 7 (100 g/l, H₂O, 20 °C) (slurry)
Bulk density 200 - 800 kg/m3
Toxicological Information
LD 50 dermal LD50 Rabbit > 5000 mg/kg
Safety Information according to GHS
Precautionary Statement(s) P260: Do not breathe dust.
Storage class 10 - 13 Other liquids and solids
WGK NWG not water endangering
Disposal 32
Chromatographic residues: Aggressive, explosive (e.g. peroxides) or toxic substances in chromatographic layers or sorbents must be eliminated using suitable methods (washing out, elution) prior to disposal. The solvents used for elution can in many cases be reutilized. Larger quantities of sorbents (e.g. from columns) should be freed from solvents (filtration, drying) and packed into rip-resistant plastic sachets; container I. TLC carrier materials and columns should be disposed of together with the corresponding waste materials (aluminium, glass, plastic); container K.

Storage and Shipping Information
Storage Storage temperature: no restrictions.